The table below shows an outline of the material we plan to cover each week. Students do not need to read ahead of lecture, however after each class should review the covered topics from the Scientific Methods for Health Sciences EBook. Each weeek, we meet once for a 3-hour lecture (Mondays) and once separately for a 1-hour discussion (Wednesdays). During face-to-face class time, we will try to cover most sections listed around that date. The daily breakdown of topics is provides to aid students that may prefer to have a more structured self-guided study plan.

HS 851 Fall'14 Week	Dates	Monday	Wednesday	Friday
1	9/1/2014	Syllabus	Inference Fundamentals	1,2, or k sample parametric inference
Course Overview		Homepage	Power, ROC Curve, sample-size, effect-size, sensitivity, specificity	mean, proportion, variance
Review		Gradebook, Expectations, HWs, Projects
Parametric Inference
2	9/8/2014	Fundamentals	Rules	Simulations
Review
Probability Theory				HW1 Due
3	9/15/2014	Discrete	Continuous	Normal Models/Inference
Review				Multi-modal/mixtures
Distributions
4	9/22/2014	Study of causation and causal inference	Measures of Occurrence, Association, and Interaction	Clinical description of disease occurrences and associated factors
Epidemiology			Prevention and Control (NNT)
				HW2 Due
5	9/29/2014	Correlation and Regression	MLR	ANOVA
Correlation/SLR/MLR
ANOVA
6	10/6/2014	MoM, MLE Estimation	CIs	Chi-Square Goodness of Fit Test
Point/Interval Estimation (CI) – MoM, MLE
Chi-Square goodness of fit test				HW3 Due
7	10/13/2014 (Study Break)	1 or 2 Sample Medians	Variances	Median Differences of more than 2 Samples
Non-parametric inference		Proportions
			Midterm Review
8	10/20/2014 Midterm	Projects, Data, Foci, Expectations	Paper Selection, Critiques
Select Papers to Review		Common mistakes and misconceptions in using probability and statistics, identifying potential assumption violations, and avoiding them	Common mistakes and misconceptions in using probability and statistics, identifying potential assumption violations, and avoiding them
Select Research Projects
Common mistakes and misconceptions in using probability and statistics, identifying potential assumption violations, and avoiding them
9	10/27/2014	Internal-Consistency Methods	Internal-Consistency Methods	Interrater Reliability
Cronbach's α		Kuder-Richardson Formulas	Cronbach's α	Applications
Measurement Reliability/Validity
Instrument performance Evaluation
10	11/3/2014	Hazard Ratios	Density, CDF, Hazard, and Survival Functions	Exponential (constant Hazard) and Weibull Model (Linear with time Hazard) Densities
Survival Analysis		Survival Analysis Goals	Censoring
Decision Theory				HW4 Due
11	11/10/2014	PCA	ICA	Factor Analysis
PCA/ICA/Factor Analysis
12	11/17/2014	Clustering	Classification
Clustering and Classification
				HW5 Due
13	11/24/2014	Imaging Statistics	Derived Imaging Biomarkers	Graphical Workflow Analyses
Applications
14	12/1/2014	Paper Review Presentations	Paper Review Presentations	Paper Review Presentations
Paper Review Presentations		3x20-min	3x20-min	3x20-min
15	12/8/2014	Research Project Presentations	Research Project Presentations	Research Project Presentations
Research Project Presentations		3x20-min	3x20-min	3x20-min
3x3x20-min
Final	12/15/2014		TBD