Homework 3: Form a group of 2 or 3 students (there should be two groups of 2 and one group of 3 students). Each group should pick one of the three case-studies below. Please avoid overlaps, first come-first serve. Coordinate groups and group case-study choices. The group should review the case-study, go deeper in to the provenance of the study, review study goals, design, data, approaches and findings and give an in-class presentation (30-min + Q&A). Try to frame the case-study in methodological terms synergizing with some of the techniques we discuss in class. Although there are significant details about each case-study, you are encouraged to research the study further. Each group will submit their slides and report (all members independently submit the same files on Canvas) and present the report in class (around the due date). Examples of themes to cover in your report/presentation include:

• Describe the study in detail.
• Why was this study undertaken? Summarize the goals.
• What were the study design, data and approach?
• What are the study outcomes, clinically-relevant contributions, and healthcare impact?
• In retrospect, are there aspects of the study that could have been done differently?
• How can the study be extended? What would you do next?

Case-Studies:

• Case-Study 1: The Cetuximab Study
• Case-Study 2: The Rosiglitazone Study
• Case-Study 3: The Nurses’ Health Study

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